Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965787 | 0.98 | NPC1 (0.50) | NPC1RAB9ACYP2D6L3MBTL1TP53 | |
| SCHEMBL5944511 | 0.98 | NPC1 (0.50) | NPC1RAB9ACYP2D6L3MBTL1TP53 | |
| SCHEMBL5289149 | 0.89 | CYP2D6 (0.40) | NPC1RAB9ACYP2D6TP53CHRNA7 | |
| SCHEMBL5290866 | 0.87 | CYP2D6 (0.39) | NPC1RAB9ACYP2D6TP53HTT | |
| SCHEMBL5944606 | 0.87 | NPC1 (0.41) | NPC1RAB9ACYP2D6L3MBTL1TP53 | |
| SCHEMBL8965305 | 0.87 | NPC1 (0.41) | NPC1RAB9ACYP2D6L3MBTL1TP53 | |
| SCHEMBL5304967 | 0.86 | DNM1 (0.40) | NPC1RAB9ACYP2D6TP53HTT | |
| SCHEMBL5290733 | 0.86 | DNM1 (0.40) | NPC1RAB9ACYP2D6TP53HTT | |
| SCHEMBL5817360 | 0.86 | DNM1 (0.40) | NPC1RAB9ACYP2D6TP53HTT | |
| SCHEMBL5301390 | 0.86 | DNM1 (0.40) | NPC1RAB9ACYP2D6TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006418-A1 | IONIC-LIQUID-CONTAINING PRODUCTS FOR DYEING AND/OR BRIGHTENING KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-01-18 | — | — | WO | disclosed |
| WO-2006131234-A1 | COSMETIC COMPOSITIONS COMPRISING IONIC LIQUIDS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-12-14 | — | — | WO | disclosed |
| US-20060186419-A1 | Light-emitting device | KABUSHIKI KAISHA TOSHIBA (JP) | 2006-08-24 | — | — | US | disclosed |