Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 11/20 | 0.38 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3531293 | 0.86 | DPP4 (0.42) | CRHR1SHMT1SHMT2ALPLDPP4 | |
| SCHEMBL3260212 | 0.85 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL3536230 | 0.83 | DPP4 (0.40) | CRHR1ALPLCNR1DPP4SMN1; SMN2 | |
| SCHEMBL5749050 | 0.81 | EGLN2 (0.35) | CRHR1 | |
| SCHEMBL5774051 | 0.81 | EGLN2 (0.35) | CRHR1 | |
| SCHEMBL3538350 | 0.80 | SCN9A (0.41) | ALPLCNR1DPP4 | |
| SCHEMBL5291917 | 0.79 | CNR1 (0.37) | CRHR1SHMT1SHMT2ALPLCNR1 | |
| SCHEMBL4019201 | 0.77 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL5768799 | 0.74 | EGLN2 (0.37) | — | |
| SCHEMBL4018674 | 0.73 | NPSR1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853607-A2 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006087120-A2 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2006-08-24 | — | — | WO | disclosed |