Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260212 | 0.92 | CRHR1 (0.33) | CRHR1TYK2IRAK4CDK2PDE4B | |
| SCHEMBL3258832 | 0.87 | CRHR1 (0.35) | CRHR1TYK2 | |
| SCHEMBL2794165 | 0.85 | ALDH1A1 (0.39) | CRHR1TYK2IRAK4PDE4B | |
| SCHEMBL2796083 | 0.84 | KDM4E (0.38) | TYK2IRAK4PDE4B | |
| SCHEMBL2794767 | 0.80 | IRAK4 (0.37) | TYK2IRAK4 | |
| SCHEMBL4017079 | 0.80 | CRHR1 (0.35) | CRHR1TYK2 | |
| SCHEMBL5290255 | 0.77 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL3262058 | 0.73 | CYP2C19 (0.37) | — | |
| SCHEMBL5291917 | 0.73 | CNR1 (0.37) | CRHR1 | |
| SCHEMBL5768799 | 0.70 | EGLN2 (0.37) | IRAK4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014661-A1 | Hererocyclically substituted heterocyclic carboxylic acid derivates | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |