SCHEMBL5292273

SCHEMBL5292273

[Li]CCCCOCCCN(C)C

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TSHR P16473 1/20 0.39
KDM4E B2RXH2 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HRH3 Q9Y5N1 4/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
DNM1 Q05193 3/20 0.33
LSS P48449 2/20 0.33
HTR1B P28222 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5274804 0.93 ALDH1A1 (0.41) ALDH1A1TSHRKDM4ESMN1; SMN2HRH3
SCHEMBL9651294 0.87 ALDH1A1 (0.50) ALDH1A1TSHRKDM4ESMN1; SMN2HRH3
SCHEMBL22813038 0.85 ALDH1A1 (0.56) ALDH1A1TSHRKDM4ESMN1; SMN2HRH3
SCHEMBL530011 0.84 ALDH1A1 (0.53) ALDH1A1TSHRKDM4ESMN1; SMN2HRH3
SCHEMBL5279475 0.83 CA12 (0.41) ALDH1A1TSHRKDM4EDNM1
SCHEMBL7763390 0.82 ALDH1A1 (0.59) ALDH1A1TSHRKDM4ESMN1; SMN2HRH3
SCHEMBL10566857 0.82 ALDH1A1 (0.50) ALDH1A1TSHRKDM4ESMN1; SMN2HRH3
SCHEMBL623374 0.82 ALDH1A1 (0.50) ALDH1A1TSHRKDM4ESMN1; SMN2HRH3
SCHEMBL4602900 0.79 ALDH1A1 (0.65) ALDH1A1TSHRKDM4ESMN1; SMN2DNM1
SCHEMBL811337 0.79 ALDH1A1 (0.65) ALDH1A1TSHRKDM4ESMN1; SMN2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030114611-A1 Functionalized alkyllithium formulations with improved thermal stability and processes for making the same FMC CORPORATION 2003-06-19 US claimed
US-20030114592-A1 Processes for improving stability of living polymer chain ends FMC CORPORATION 2003-06-19 US claimed
US-20030032746-A1 Hetero-telechelic polymers and processes for making same FMC CORPORATION 2003-02-13 US claimed
US-20030032745-A1 Hetero-telechelic polymers and processes for making same SCHWINDEMAN JAMES A (US) 2003-02-13 US claimed
US-20030013827-A1 Hetero-telechelic polymers and processes for making same FMC CORPORATION 2003-01-16 US claimed
EP-0842199-B1 HETERO-TELECHELIC POLYMERS AND PROCESSES FOR MAKING SAME FMC CORP (US) 2002-04-03 EP claimed
US-6221991-B1 STAR POLYMER FMC CORPORATION 2001-04-24 US claimed
WO-2000050478-A1 NOVEL FORMULATIONS OF ALKYLLITHIUMS WITH IMPROVED THERMAL STABILITY, PROCESSES TO PRODUCE THESE FORMULATIONS AND PROCESSES FOR USING THE SAME TO IMPROVE STABILITY OF LIVING POLYMER CHAIN ENDS FMC CORPORATION (US) 2000-08-31 WO claimed
EP-0842199-A1 HETERO-TELECHELIC POLYMERS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1998-05-20 EP claimed
WO-1997006192-A1 FUNCTIONALIZED POLYSTYRENE/POLYDIENE COPOLYMERS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1997-02-20 WO claimed
WO-1997006188-A1 TELECHELIC POLYSTYRENE/POLYETHYLENE COPOLYMERS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1997-02-20 WO claimed
WO-1997005174-A1 HETERO-TELECHELIC POLYMERS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1997-02-13 WO claimed
WO-1997005173-A1 METHACRYLATE AND ACRYLATE POLYMERS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1997-02-13 WO claimed
EP-0827423-B1 FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORP (US) 2007-12-12 EP disclosed
US-6703446-B2 POLYMERS HAVING DIFFERENT FUNCTIONALITIES AT OPPOSITE ENDS OF THE POLYMER CHAIN; CAN BE COPOLYMERIZED WITH OTHER MONOMERS TO PROVIDE NOVEL COPOLYMERS POSSESSING A WIDE RANGE OF PHYSICAL PROPERTIES FMC CORPORATION, LITHIUM DIVISION 2004-03-09 US disclosed
US-6699939-B2 POLYMERS HAVING DIFFERENT FUNCTIONALITIES AT OPPOSITE ENDS OF THE POLYMER CHAIN; CAN BE COPOLYMERIZED WITH OTHER MONOMERS TO PROVIDE NOVEL COPOLYMERS POSSESSING A WIDE RANGE OF PHYSICAL PROPERTIES FMC CORPORATION, LITHIUM DIVISION 2004-03-02 US disclosed
WO-1997005174-A1 HETERO-TELECHELIC POLYMERS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1997-02-13 WO disclosed
WO-1997005176-A1 DEPROTECTION OF PROTECTED FUNCTIONAL POLYMERS FMC CORPORATION (US) 1997-02-13 WO disclosed
WO-1997005173-A1 METHACRYLATE AND ACRYLATE POLYMERS AND PROCESSES FOR MAKING SAME FMC CORPORATION (US) 1997-02-13 WO disclosed
WO-1996035509-A1 FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORPORATION (US) 1996-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114611-A1 Functionalized alkyllithium formulations with improved thermal stability and processes for making the same AAAS, AS3MT, APC ALDH1A1 1472/4885TSHR 2597/4885KDM4E 2345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.