Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476011 | 0.85 | TSHR (0.44) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL27542979 | 0.84 | TSHR (0.40) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL5297547 | 0.83 | TSHR (0.42) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL17114710 | 0.83 | ALDH1A1 (0.45) | TSHRTHRBALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5716610 | 0.82 | TSHR (0.41) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL3477341 | 0.82 | TSHR (0.50) | TSHRTHRBHCAR2ALDH1A1DGKA | |
| SCHEMBL5310141 | 0.80 | — | — | |
| SCHEMBL2951935 | 0.80 | TSHR (0.40) | TSHRTHRBHCAR2ALDH1A1GAA | |
| SCHEMBL11142420 | 0.80 | TSHR (0.53) | TSHRALDH1A1ESR1TDP1DGKA | |
| SCHEMBL18007115 | 0.80 | FFAR3 (0.41) | TSHRTHRBHCAR2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007332-A1 | TRIBROMONEOPENTYL (METH)ACRYLATE BASED COPOLYMERS AND LENSES MADE THEREFROM | H.P.O.P - HIGH PERFORMANCE OPTICAL POLYMERS LTD. (IL) | 2007-01-18 | — | — | WO | disclosed |