Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535763 | 0.87 | CYP2D6 (0.51) | CYP2D6CYP2C19ALDH1A1TRPA1GLO1 | |
| SCHEMBL14616293 | 0.87 | CYP2D6 (0.51) | CYP2D6CYP2C19ALDH1A1TRPA1GLO1 | |
| SCHEMBL1759140 | 0.87 | CYP2D6 (0.51) | CYP2D6CYP2C19ALDH1A1TRPA1GLO1 | |
| SCHEMBL11330538 | 0.85 | CYP2D6 (0.40) | CYP2D6CYP2C19ALDH1A1GLO1LMNA | |
| SCHEMBL27621557 | 0.85 | CYP2D6 (0.40) | CYP2D6CYP2C19ALDH1A1GLO1LMNA | |
| SCHEMBL25236003 | 0.82 | MGLL (0.38) | CYP2D6CYP2C19ALDH1A1GLO1TSHR | |
| SCHEMBL7087296 | 0.82 | ALDH1A1 (0.52) | CYP2D6CYP2C19ALDH1A1TSHRATM | |
| SCHEMBL28152436 | 0.82 | TSHR (0.52) | CYP2D6CYP2C19ALDH1A1GLO1GRIK1 | |
| SCHEMBL9114588 | 0.81 | CYP2D6 (0.40) | CYP2D6CYP2C19GRIK1GRIK2 | |
| SCHEMBL9113423 | 0.80 | ALDH1A1 (0.40) | CYP2D6CYP2C19ALDH1A1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007332-A1 | TRIBROMONEOPENTYL (METH)ACRYLATE BASED COPOLYMERS AND LENSES MADE THEREFROM | H.P.O.P - HIGH PERFORMANCE OPTICAL POLYMERS LTD. (IL) | 2007-01-18 | — | — | WO | disclosed |