Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418206 | 1.00 | ACP3 (0.46) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL1664227 | 1.00 | ACP3 (0.46) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL12797131 | 0.88 | CYP2A6 (0.42) | ACP3ANPEPCYP2A6IDO1 | |
| SCHEMBL7028553 | 0.84 | HTR2A (0.52) | ACP3RETHTR2AIDO1PDPK1 | |
| SCHEMBL2278230 | 0.81 | ANPEP (0.59) | HTR2AANPEP | |
| SCHEMBL9385590 | 0.78 | ACP3 (0.48) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL7124003 | 0.77 | ACP3 (0.47) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL8901794 | 0.77 | ACP3 (0.47) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL948086 | 0.75 | ACP3 (0.46) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL29633441 | 0.75 | ANPEP (0.68) | ACP3RETHTR2AANPEPIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012015944-A2 | NOVEL TETRAHYDRONAPHALENE ANTAGONISTS TO THE THROMBOXANE A2 (TP) RECEPTOR | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-02-02 | — | — | WO | disclosed |