Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529484 | 1.00 | ACP3 (0.46) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL29418206 | 1.00 | ACP3 (0.46) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL12797131 | 0.88 | CYP2A6 (0.42) | ACP3ANPEPCYP2A6IDO1 | |
| SCHEMBL7028553 | 0.84 | HTR2A (0.52) | ACP3RETHTR2AIDO1PDPK1 | |
| SCHEMBL2278230 | 0.81 | ANPEP (0.59) | HTR2AANPEP | |
| SCHEMBL9385590 | 0.78 | ACP3 (0.48) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL7124003 | 0.77 | ACP3 (0.47) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL8901794 | 0.77 | ACP3 (0.47) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL948086 | 0.75 | ACP3 (0.46) | ACP3RETHTR2AANPEPCES1 | |
| SCHEMBL29633441 | 0.75 | ANPEP (0.68) | ACP3RETHTR2AANPEPIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851549-B | 5-hydrogen-benzo [ b ] carbazole and related derivatives and synthetic method thereof | 西安欧得光电材料有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-105777710-B | A kind of Ai Le replaces the synthetic method of Buddhist nun | 湖南欧亚药业有限公司 | 2018-09-04 | — | — | CN | claimed |
| CN-107619386-A | A kind of aromatic ring simultaneously [c] carbazole analog derivative and its synthetic method | 湘潭大学 | 2018-01-23 | — | — | CN | claimed |
| CN-104591988-A | Method for synthesizing 6-bromo-2-tetralone | GANSU RES INST OF CHEMICAL INDUSTRY | 2015-05-06 | — | — | CN | claimed |
| EP-4168417-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | Idemitsu Kosan Co., Ltd (JP) | 2023-04-26 | — | — | EP | disclosed |
| CN-109851549-B | 5-hydrogen-benzo [ b ] carbazole and related derivatives and synthetic method thereof | 西安欧得光电材料有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-109851549-B | 5-hydrogen-benzo [ b ] carbazole and related derivatives and synthetic method thereof | 西安欧得光电材料有限公司 | 2022-03-29 | — | — | CN | disclosed |
| WO-2021255698-A1 | HETEROCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE HETEROCYCLIC COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2021-12-23 | — | — | WO | disclosed |
| CN-109851549-A | A kind of 5- hydrogen-benzo [b] carbazole and related derivatives and its synthetic method | 西安欧得光电材料有限公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-108699058-A | Heterofused phenylquinazolines and their use in electronic devices | 出光兴产株式会社 | 2018-10-23 | — | — | CN | disclosed |
| CN-105777710-B | A kind of Ai Le replaces the synthetic method of Buddhist nun | 湖南欧亚药业有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-107619386-A | A kind of aromatic ring simultaneously [c] carbazole analog derivative and its synthetic method | 湘潭大学 | 2018-01-23 | — | — | CN | disclosed |
| EP-2482661-A1 | REVERSED BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | Schering Corporation (US) | 2012-08-08 | — | — | EP | disclosed |
| US-20110251207-A1 | BIARYL-SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA 2C ADRENERGIC RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2011-10-13 | — | — | US | disclosed |
| EP-2356106-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | Schering Corporation (US) | 2011-08-17 | — | — | EP | disclosed |
| WO-2011041181-A1 | REVERSED BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2011-04-07 | — | — | WO | disclosed |
| WO-2010042473-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010042475-A1 | SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |
| EP-0975583-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998045252-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1998-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251207-A1 | BIARYL-SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA 2C ADRENERGIC RECEPTOR MODULATORS | ADRA2C, ADRB2, ADRB3 | ACP3 3516/4885RET 1796/4885HTR2A 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.