Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528856 | 0.92 | MAPT (0.49) | MAPTNPSR1LMNAMEN1KMT2A | |
| SCHEMBL528329 | 0.91 | MAPT (0.47) | MAPTNPSR1LMNAMEN1KMT2A | |
| SCHEMBL528857 | 0.90 | SMN1; SMN2 (0.56) | MAPTNPSR1LMNAMEN1KMT2A | |
| SCHEMBL528084 | 0.90 | SMN1; SMN2 (0.56) | MAPTNPSR1LMNAMEN1KMT2A | |
| SCHEMBL528794 | 0.90 | MAPT (0.62) | MAPTLMNAKMT2AHTTALDH1A1 | |
| SCHEMBL527890 | 0.89 | MAPT (0.62) | MAPTNPSR1LMNAMEN1KMT2A | |
| SCHEMBL528788 | 0.86 | MAPT (0.54) | MAPTNPSR1LMNAMEN1KMT2A | |
| SCHEMBL528754 | 0.85 | MAPT (0.56) | MAPTNPSR1LMNAMEN1KMT2A | |
| SCHEMBL529349 | 0.85 | MAPT (0.61) | MAPTNPSR1LMNAMEN1KMT2A | |
| SCHEMBL529287 | 0.84 | KMT2A (0.64) | MAPTNPSR1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |