Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528293 | 0.92 | MAPT (0.59) | MAPTLMNAKDM4EALDH1A1NR3C1 | |
| SCHEMBL529032 | 0.90 | MAPT (0.77) | MAPTLMNAKDM4EALDH1A1NR3C1 | |
| SCHEMBL529548 | 0.90 | MAPT (0.52) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL528856 | 0.89 | MAPT (0.49) | MAPTLMNAALDH1A1KMT2AHTT | |
| SCHEMBL528329 | 0.87 | MAPT (0.47) | MAPTLMNAALDH1A1KMT2AHTT | |
| SCHEMBL529003 | 0.87 | MAPT (0.66) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL528590 | 0.86 | MAPT (0.63) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL528683 | 0.86 | MAPT (0.77) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL528499 | 0.84 | MAPT (0.63) | MAPTLMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL527969 | 0.84 | MAPT (0.60) | MAPTLMNAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |