Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.50 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966860 | 1.00 | FAAH (0.70) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL5966857 | 1.00 | FAAH (0.70) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL9377518 | 0.94 | FAAH (0.78) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL5936930 | 0.94 | FAAH (0.78) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL101698 | 0.94 | FAAH (0.78) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL15649884 | 0.92 | FAAH (0.81) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL12349998 | 0.92 | FAAH (0.81) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL342410 | 0.92 | FAAH (0.81) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL17203936 | 0.92 | FAAH (0.81) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 | |
| SCHEMBL12350003 | 0.92 | FAAH (0.81) | FAAHSMN1; SMN2SLC6A5MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432039-A2 | Antipsychotic drug comprising an acylaminoacid | NIPPON OILS & FATS CO., LTD. (JP) | 1991-06-12 | — | — | EP | claimed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
| US-5112863-A | N-Acyl Amino Acid Derivative | NIPPON OIL & FATS CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0432039-A2 | Antipsychotic drug comprising an acylaminoacid | NIPPON OILS & FATS CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | FAAH 3814/4885SMN1; SMN2 3894/4885SLC6A5 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.