Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | PTGFR | P43088 | 2/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528042 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL528043 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4210528 | 0.70 | KDM4E (0.59) | GAAPKMAKR1C3AKR1C2PIM2 | |
| SCHEMBL4210529 | 0.70 | KDM4E (0.59) | GAAPKMAKR1C3AKR1C2PIM2 | |
| SCHEMBL15940701 | 0.68 | CA1 (0.43) | GAAPTGER3PTGER2PTGER1PTGER4 | |
| SCHEMBL31026896 | 0.68 | CA1 (0.43) | GAAPTGER3PTGER2PTGER1PTGER4 | |
| SCHEMBL15940704 | 0.68 | CA1 (0.43) | GAAPTGER3PTGER2PTGER1PTGER4 | |
| SCHEMBL15381411 | 0.66 | IRAK4 (0.44) | — | |
| SCHEMBL6958095 | 0.66 | ALOX5 (0.65) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3778055 | 0.66 | MIF (0.41) | GAAPTGER3PTGER2PTGER1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | Oryzon Genomics, S.A. (ES) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012013727-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |