SCHEMBL5297552

SCHEMBL5297552

C=C(CCC)C(=O)OCBr

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
TSHR P16473 5/20 0.35
HDAC3 O15379 4/20 0.35
HDAC1 Q13547 4/20 0.35
HDAC2 Q92769 4/20 0.35
HDAC8 Q9BY41 4/20 0.35
FFAR3 O14843 3/20 0.35
TRPA1 O75762 1/20 0.34
THRB P10828 1/20 0.32
HDAC6 Q9UBN7 1/20 0.31
DGKA P23743 1/20 0.30
CTSD P07339 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3423721 0.84 THRB (0.47) ALDH1A1CES2CES1TSHRHDAC3
SCHEMBL375086 0.84 ALDH1A1 (0.48) ALDH1A1CES2CES1TSHRHDAC3
SCHEMBL3476011 0.82 TSHR (0.44) ALDH1A1CES2CES1TSHRHDAC3
SCHEMBL27529430 0.82 ALDH1A1 (0.37) ALDH1A1CES2CES1TSHRHDAC3
SCHEMBL3838445 0.81
SCHEMBL9244631 0.80 ALDH1A1 (0.36) ALDH1A1CES2CES1TSHRHDAC3
SCHEMBL8219079 0.80 TSHR (0.37) ALDH1A1CES2CES1TSHRHDAC3
SCHEMBL28885925 0.79 ALDH1A1 (0.39) ALDH1A1CES2CES1TSHRHDAC3
SCHEMBL3477377 0.78 TSHR (0.55) ALDH1A1TSHRTHRBDGKA
SCHEMBL16320055 0.78 TSHR (0.35) ALDH1A1CES2CES1TSHRHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113329693-A Laminated manufacture of radiological prostheses 斯特拉塔西斯公司 2021-08-31 CN disclosed
WO-2007007332-A1 TRIBROMONEOPENTYL (METH)ACRYLATE BASED COPOLYMERS AND LENSES MADE THEREFROM H.P.O.P - HIGH PERFORMANCE OPTICAL POLYMERS LTD. (IL) 2007-01-18 WO disclosed