SCHEMBL5297574

SCHEMBL5297574

N#Cc1ccc(OCCOc2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.66
ALDH1A1 P00352 2/20 0.58
MAPT P10636 1/20 0.58
KCNA3 P22001 1/20 0.56
MMP2 P08253 2/20 0.56
TSHR P16473 1/20 0.54
PKM P14618 1/20 0.52
HRH3 Q9Y5N1 2/20 0.50
TAAR1 Q96RJ0 1/20 0.50
RECQL P46063 1/20 0.50
KCNA5 P22460 1/20 0.49
PARP10 Q53GL7 1/20 0.48
LTA4H P09960 2/20 0.48
PLA2G2A P14555 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
MMP1 P03956 1/20 0.47
MMP3 P08254 1/20 0.47
MMP9 P14780 1/20 0.47
MMP13 P45452 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280900 0.94 KCNA3 (0.67) MAOBALDH1A1MAPTKCNA3MMP2
SCHEMBL1777722 0.92 KCNA3 (0.64) MAOBALDH1A1MAPTKCNA3MMP2
SCHEMBL7986752 0.91 ALDH1A1 (0.66) MAOBALDH1A1MAPTMMP2HRH3
SCHEMBL5836533 0.87 MAOB (0.66) MAOBALDH1A1MAPTKCNA3MMP2
SCHEMBL8673505 0.84 SMN1; SMN2 (0.61) MAOBALDH1A1MAPTMMP2HRH3
SCHEMBL3714917 0.84 MAOB (0.68) MAOBMMP2LTA4H
SCHEMBL7425998 0.84 MAOB (0.58) MAOBKCNA3MMP2TSHRLTA4H
SCHEMBL5519875 0.84 HRH3 (0.62) MAOBALDH1A1MAPTMMP2HRH3
SCHEMBL7384498 0.84 HRH3 (0.59) MAOBALDH1A1MAPTMMP2HRH3
SCHEMBL8053774 0.84 DRD4 (0.73) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
US-20060293181-A1 Thermal recording materials and methods of making and using the same NASHUA CORPORATION 2006-12-28 US disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed
US-RE36321-E INCLUDING DIARYL DIETHER COMPOUND KANSAKI PAPER MANUFACTURING CO., LTD. (JP) 1999-09-28 US disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed
EP-0141170-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-05-15 EP disclosed