Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28265726 | 0.81 | POLB (0.48) | HTR6LTA4HPOLBHTR2A | |
| SCHEMBL6796105 | 0.80 | HTR6 (0.55) | HTR6POLBHTR2A | |
| SCHEMBL18019793 | 0.80 | HTR6 (0.55) | HTR6POLBHTR2A | |
| SCHEMBL18019790 | 0.80 | HTR6 (0.55) | HTR6POLBHTR2A | |
| SCHEMBL4282739 | 0.79 | SLC6A4 (0.42) | HTR2AIDO1 | |
| Hydrochloric Acid SCHEMBL17979687 | 0.79 | HTR6 (0.56) | HTR6POLBHTR2A | |
| SCHEMBL27636075 | 0.79 | HSD17B10 (0.44) | HTR6 | |
| SCHEMBL12244120 | 0.78 | HTR6 (0.68) | HTR6HTR2A | |
| SCHEMBL12244098 | 0.77 | HTR6 (0.67) | HTR6 | |
| SCHEMBL13809136 | 0.77 | LTA4H (0.66) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108976227-A | Benzothiazine -4- ketone compounds containing alkaline bridged ring segment and preparation method thereof | 浙江司太立制药股份有限公司 | 2018-12-11 | — | — | CN | disclosed |
| WO-2007027734-A2 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX, INC. (US) | 2007-03-08 | — | — | WO | disclosed |