Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20552421 | 0.91 | BCAT2 (0.50) | BCAT2BRD4MKNK1MKNK2KDM4E | |
| SCHEMBL6389902 | 0.87 | BCAT2 (0.47) | BCAT2BRD4MKNK1MKNK2KDM4E | |
| SCHEMBL28727078 | 0.87 | FABP4 (0.45) | BRD4MKNK1MKNK2KMT2AFABP4 | |
| SCHEMBL27911586 | 0.86 | BCAT2 (0.55) | BCAT2BRD4MKNK1MKNK2KDM4E | |
| Dimethylamine SCHEMBL9280041 | 0.86 | BCAT2 (0.46) | BCAT2BRD4MKNK1MKNK2KDM4E | |
| SCHEMBL28784266 | 0.84 | BCAT2 (0.44) | BCAT2BRD4KDM4EMEN1KMT2A | |
| SCHEMBL3834197 | 0.84 | KMT2A (0.50) | BCAT2BRD4MKNK1MKNK2KDM4E | |
| SCHEMBL27475690 | 0.84 | BCAT2 (0.47) | BCAT2BRD4MKNK1MKNK2KDM4E | |
| SCHEMBL7430279 | 0.84 | FABP4 (0.43) | BCAT2BRD4MKNK1MKNK2FABP4 | |
| SCHEMBL529885 | 0.82 | DHODH (0.46) | BCAT2BRD4MKNK1MKNK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |