Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.55 |
| ▸ | KIT | P10721 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | BCR | P11274 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27512966 | 0.83 | CA2 (0.55) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL32666155 | 0.77 | FLT3 (0.59) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL6019304 | 0.77 | CYP2A6 (0.63) | AOC3GAAALOX15PLAUEHMT2 | |
| SCHEMBL2454392 | 0.77 | FLT3 (0.59) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL12348 | 0.74 | CYP2A6 (0.59) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL12778106 | 0.74 | FLT3 (0.55) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL28745423 | 0.74 | FLT3 (0.55) | FLT3PDGFRBKITABL1BCR | |
| SCHEMBL5706427 | 0.74 | AOC3 (0.54) | FLT3AOC3EHMT2HRH4 | |
| SCHEMBL1465978 | 0.74 | LOXL2 (0.58) | FLT3AOC3ALOX15EHMT2HRH4 | |
| SCHEMBL29042581 | 0.74 | AOC3 (0.54) | CA2AOC3EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10222390-B2 | Near-infrared fluorescent sensors for biological amines | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170082645-A1 | NEAR-INFRARED FLUORESCENT SENSORS FOR BIOLOGICAL AMINES | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2017-03-23 | — | — | US | disclosed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | disclosed |
| CN-102127058-A | Pyrimidine derivatives for the treatment of abnormal cell growth | PFIZER PROD INC | 2011-07-20 | — | — | CN | disclosed |
| CN-1953974-A | Pyrimidine derivatives for the treatment of abnormal cell growth | PFIZER (US) | 2007-04-25 | — | — | CN | disclosed |
| CN-1250526-C | Pyrrole substituted 2-indolinone protein kinase inhibitors | SUGEN INC (US) | 2006-04-12 | — | — | CN | disclosed |
| CN-1311775-A | Pyrrole substituted 2-indolinone protein kinase inhibitors | SUGEN INC (US) | 2001-09-05 | — | — | CN | disclosed |