Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130196 | 0.81 | HTT (0.54) | KMT2AMEN1PABPC1KDM4EMAPT | |
| SCHEMBL4126374 | 0.79 | SMN1; SMN2 (0.52) | KMT2AMEN1PABPC1KDM4EMAPT | |
| SCHEMBL6846376 | 0.77 | KMT2A (0.58) | KMT2AMEN1PABPC1KDM4EMAPT | |
| SCHEMBL10417850 | 0.77 | KMT2A (0.58) | KMT2AMEN1PABPC1KDM4EMAPT | |
| SCHEMBL4126551 | 0.76 | NAMPT (0.48) | KMT2AMEN1PABPC1KDM4EMAPT | |
| SCHEMBL4119204 | 0.76 | NPC1 (0.48) | KMT2AMEN1PABPC1KDM4EMAPT | |
| SCHEMBL4132024 | 0.76 | KMT2A (0.43) | KMT2AMEN1PABPC1KDM4EMAPT | |
| Cyclopropane SCHEMBL8126236 | 0.76 | NPC1 (0.56) | KMT2AMEN1PABPC1KDM4EMAPT | |
| SCHEMBL2397341 | 0.75 | RAB9A (0.58) | KMT2AMEN1PABPC1KDM4EMAPT | |
| SCHEMBL4386794 | 0.75 | ALDH1A1 (0.47) | KMT2AMEN1PABPC1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841758-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS | Pfizer Limited (GB) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077496-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS | PFIZER LIMITED (GB) | 2006-07-27 | — | — | WO | disclosed |