Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 10/20 | 0.50 |
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA9 | Q16790 | 8/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002519 | 0.89 | TSHR (0.74) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL372403 | 0.89 | — | — | |
| SCHEMBL17334965 | 0.87 | TSHR (0.54) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| Fluoride SCHEMBL28098238 | 0.86 | TSHR (0.70) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL27903035 | 0.86 | TSHR (0.70) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL27779386 | 0.86 | TSHR (0.70) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| Ammonia Solution, Strong SCHEMBL28151887 | 0.86 | TSHR (0.70) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL5049329 | 0.86 | — | — | |
| SCHEMBL28832743 | 0.86 | TSHR (0.70) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL11980487 | 0.84 | TSHR (0.75) | ALDH1A1TSHRLMNAKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008143-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |