Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5301209 | 0.91 | HCAR2 (0.59) | ALDH1A1MAPTMAPK1GAAHCAR2 | |
| SCHEMBL5061223 | 0.89 | KDM4E (0.62) | ALDH1A1KDM4EHCAR2NPC1RAB9A | |
| SCHEMBL5296892 | 0.89 | HCAR2 (0.67) | ALDH1A1KDM4EGAAHCAR2RAB9A | |
| SCHEMBL5303071 | 0.87 | KDM4E (0.50) | ALDH1A1KDM4EHCAR2HDAC1NPC1 | |
| SCHEMBL5300871 | 0.85 | KDM4E (0.48) | ALDH1A1MAPTKDM4EHCAR2HDAC1 | |
| SCHEMBL5302379 | 0.84 | KDM4E (0.54) | ALDH1A1KDM4EGAAHDAC1TSHR | |
| SCHEMBL5307245 | 0.84 | KDM4E (0.52) | ALDH1A1KDM4EGAAHCAR2MEN1 | |
| SCHEMBL5301602 | 0.82 | KDM4E (0.50) | ALDH1A1MAPTMAPK1KDM4EHCAR2 | |
| SCHEMBL5297607 | 0.81 | HCAR2 (0.62) | ALDH1A1KDM4EHCAR2TSHRNPC1 | |
| SCHEMBL14609699 | 0.81 | HCAR2 (0.64) | ALDH1A1MAPTMAPK1KDM4EHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015744-A1 | DISUBSTITUTED THIENYL COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |