Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332700 | 0.76 | TSHR (0.56) | ACKR3TMEM97SIGMAR1LPAR1NPC1 | |
| SCHEMBL23607906 | 0.73 | HDAC1 (0.44) | ACKR3TMEM97SIGMAR1LPAR1LPAR5 | |
| SCHEMBL5309605 | 0.73 | CYP1A2 (0.50) | LPAR1 | |
| SCHEMBL14610645 | 0.70 | LPAR1 (0.47) | LPAR1LPAR5ROCK1 | |
| SCHEMBL5112810 | 0.68 | MRGPRX4 (0.53) | LPAR1LPAR5HDAC1HDAC6RAB9A | |
| SCHEMBL5302863 | 0.68 | LMNA (0.55) | ACKR3TMEM97SIGMAR1LPAR1NPC1 | |
| SCHEMBL3707453 | 0.66 | NAMPT (0.68) | ACKR3TMEM97SIGMAR1 | |
| SCHEMBL1810218 | 0.64 | PTPN11 (0.61) | LPAR1LPAR5HDAC1HDAC6HDAC3 | |
| SCHEMBL29694520 | 0.64 | ERN1 (0.57) | CDK1ERN1 | |
| SCHEMBL117649 | 0.64 | ERN1 (0.57) | CDK1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017092-A1 | SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |