Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610069 | 0.84 | TDP1 (0.46) | TSHRTDP1ACKR3TMEM97SIGMAR1 | |
| SCHEMBL5302863 | 0.84 | LMNA (0.55) | ACKR3TMEM97SIGMAR1NPC1MAPT | |
| SCHEMBL5304556 | 0.83 | TSHR (0.60) | TSHRTDP1NPC1MAPTHPGD | |
| SCHEMBL5300837 | 0.76 | ACKR3 (0.42) | ACKR3TMEM97SIGMAR1NPC1RAB9A | |
| SCHEMBL5327782 | 0.74 | MAPK14 (0.42) | LPAR1 | |
| SCHEMBL5303445 | 0.74 | TRPM8 (0.48) | TMEM97SIGMAR1MAPTNPSR1KDM4E | |
| SCHEMBL12354118 | 0.73 | TSHR (1.00) | TSHRTDP1MAPTHPGDALDH1A1 | |
| SCHEMBL14610068 | 0.73 | TDP1 (0.46) | TSHRTDP1TMEM97SIGMAR1 | |
| SCHEMBL14609954 | 0.72 | LMNA (0.48) | ACKR3TMEM97SIGMAR1NPC1MAPT | |
| SCHEMBL23607906 | 0.71 | HDAC1 (0.44) | ACKR3TMEM97SIGMAR1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017093-A1 | SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |