Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 8/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1806672 | 0.79 | CA1 (0.46) | PTGS2CA1CA2PTGES2PSEN1 | |
| SCHEMBL1809065 | 0.76 | PTGS2 (0.49) | PTGS2CA1CA2PTGES2PSEN1 | |
| SCHEMBL8661275 | 0.74 | PTGS2 (0.69) | PTGS2PTGS1F10CA1CA2 | |
| SCHEMBL7584026 | 0.74 | PTGS2 (0.50) | PTGS2PTGS1F10CA1CA2 | |
| SCHEMBL28362934 | 0.74 | PTGS2 (0.68) | PTGS2PTGS1F10CA1CA2 | |
| SCHEMBL1080972 | 0.73 | CA2 (0.61) | CA1CA2LDHACDK2 | |
| SCHEMBL21507851 | 0.72 | PTGDR2 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1804258 | 0.71 | CA2 (0.50) | PTGS2CA1CA2PTGES2LDHA | |
| SCHEMBL28076138 | 0.71 | PTGES2 (0.39) | F10CA1CA2PTGES2 | |
| SCHEMBL8660030 | 0.71 | PTGES2 (0.48) | PTGS2PTGS1F10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014054-A2 | BENZENESULFONAMIDE INHIBITOR OF CCR2 CHEMOKINE RECEPTOR | GLAXO GROUP LIMTED (GB) | 2007-02-01 | — | — | WO | disclosed |