Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.40 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.40 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301679 | 0.89 | BCAT2 (0.57) | BCAT2KEAP1NFE2L2SCN1ASCN2A | |
| SCHEMBL4068668 | 0.84 | BCAT2 (0.62) | BCAT2KEAP1NFE2L2HNF4APLA2G10 | |
| SCHEMBL4560226 | 0.81 | BCAT2 (0.57) | BCAT2KEAP1NFE2L2HNF4APLA2G10 | |
| SCHEMBL2564959 | 0.78 | BCAT2 (0.57) | BCAT2KEAP1NFE2L2SCN1ASCN2A | |
| SCHEMBL530130 | 0.77 | TSHR (0.45) | BCAT2KEAP1NFE2L2PLA2G10PLA2G2A | |
| SCHEMBL3079111 | 0.76 | PDCD1 (0.43) | KMT2AKCNQ2MAPT | |
| SCHEMBL4439618 | 0.75 | BCAT2 (0.62) | BCAT2KEAP1NFE2L2SCN1ASCN2A | |
| SCHEMBL3643864 | 0.75 | IRAK4 (0.37) | KEAP1NFE2L2MEN1KMT2AIRAK4 | |
| SCHEMBL28382984 | 0.74 | PDCD1 (0.41) | SMN1; SMN2NPC1RAB9AKCNQ2MAPT | |
| SCHEMBL8679944 | 0.74 | TSHR (0.48) | KCNQ2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |