Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.38 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.38 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.38 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.38 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.38 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301698 | 0.89 | BCAT2 (0.41) | BCAT2KEAP1NFE2L2IRAK4PARP1 | |
| SCHEMBL4410159 | 0.84 | BCAT2 (0.49) | TSHRBCAT2KEAP1NFE2L2IRAK4 | |
| SCHEMBL1380696 | 0.82 | TSHR (0.55) | TSHRBCAT2KEAP1NFE2L2IRAK4 | |
| SCHEMBL8526511 | 0.82 | TSHR (0.55) | TSHRBCAT2KEAP1NFE2L2IRAK4 | |
| Acetic Acid SCHEMBL8910191 | 0.82 | BCAT2 (0.46) | BCAT2KEAP1NFE2L2IRAK4PARP1 | |
| SCHEMBL4560229 | 0.81 | BCAT2 (0.45) | BCAT2KEAP1NFE2L2IRAK4PARP1 | |
| SCHEMBL28240555 | 0.79 | TSHR (0.43) | TSHRBCAT2KEAP1NFE2L2IRAK4 | |
| SCHEMBL28240556 | 0.78 | TSHR (0.46) | TSHRKEAP1NFE2L2IRAK4PARP1 | |
| SCHEMBL27214460 | 0.77 | BCAT2 (0.63) | TSHRBCAT2KEAP1NFE2L2PARP1 | |
| SCHEMBL530128 | 0.77 | BCAT2 (0.56) | BCAT2KEAP1NFE2L2IRAK4PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |