Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.62 |
| ▸ | RELA | Q04206 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 10/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12692485 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| Bromide SCHEMBL3869607 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL30059210 | 0.80 | NPC1 (0.66) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL4147815 | 0.80 | NPC1 (0.66) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL8342601 | 0.80 | MAPT (0.65) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL12970198 | 0.77 | NPC1 (0.66) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL1728599 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL969616 | 0.77 | NPC1 (0.66) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL5773733 | 0.77 | TP53 (0.68) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL1692138 | 0.77 | NPC1 (0.66) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933049-B2 | Mobilizing agents and uses therefor | THE UNIVERSITY OF QUEENSLAND (AU) | 2021-03-02 | — | — | US | disclosed |
| US-20180185328-A1 | MOBILIZING AGENTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2018-07-05 | — | — | US | disclosed |
| EP-3302710-A1 | MOBILIZING AGENTS AND USES THEREFOR | The University of Queensland (AU) | 2018-04-11 | — | — | EP | disclosed |
| WO-2016191811-A1 | MOBILIZING AGENTS AND USES THEREFOR | THE UNIVERSITY OF QUEENSLAND (AU) | 2016-12-08 | — | — | WO | disclosed |
| WO-2007034282-A2 | DIARYL-IMIDAZOLE COMPOUNDS CONDENSED WITH A HETEROCYCLE AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180185328-A1 | MOBILIZING AGENTS AND USES THEREFOR | C3AR1, CSF3R, C5AR1 | SMN1; SMN2 3345/4885NPC1 2609/4885RAB9A 2885/4885 |
| US-10933049-B2 | Mobilizing agents and uses therefor | C3AR1, CSF3R, C5AR1 | SMN1; SMN2 3345/4885NPC1 2609/4885RAB9A 2885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.