Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400517 | 1.00 | EPHX1 (0.41) | EPHX1TSHRMAPTGAAALDH1A1 | |
| SCHEMBL10034792 | 1.00 | EPHX1 (0.41) | EPHX1TSHRMAPTGAAALDH1A1 | |
| SCHEMBL6109677 | 1.00 | EPHX1 (0.41) | EPHX1TSHRMAPTGAAALDH1A1 | |
| SCHEMBL10400049 | 1.00 | EPHX1 (0.41) | EPHX1TSHRMAPTGAAALDH1A1 | |
| SCHEMBL9802330 | 0.80 | MEN1 (0.38) | MAPTGAAALDH1A1CYP2A6LMNA | |
| SCHEMBL10400428 | 0.80 | RAB9A (0.38) | MAPTALDH1A1CYP2A6LMNAMAPK1 | |
| SCHEMBL9377930 | 0.79 | LMNA (0.39) | EPHX1TSHRMAPTGAAALDH1A1 | |
| SCHEMBL10372159 | 0.79 | LMNA (0.39) | EPHX1TSHRMAPTGAAALDH1A1 | |
| SCHEMBL5057401 | 0.76 | EPHX1 (0.36) | EPHX1TSHRALDH1A1 | |
| SCHEMBL6684940 | 0.76 | EPHX1 (0.37) | EPHX1TSHRHTR2BCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005935-A2 | NOREPINEPHRINE TRANSPORTER RADIOTRACERS AND METHODS OF SYNTHESES THEREOF | MOLECULAR NEUROIMAGING, LLC (US) | 2007-01-11 | — | — | WO | disclosed |
| WO-2007005935-A2 | NOREPINEPHRINE TRANSPORTER RADIOTRACERS AND METHODS OF SYNTHESES THEREOF | MOLECULAR NEUROIMAGING, LLC (US) | 2007-01-11 | — | — | WO | disclosed |
| US-4937331-A | Chemical intermediates for antibiotics | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0334593-A1 | Chiral azetidinone epoxides | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1989-09-27 | — | — | EP | disclosed |