SCHEMBL5301792

SCHEMBL5301792

O=C(O)Oc1ccc2c(c1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.48
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
MAOA P21397 6/20 0.48
HPGD P15428 4/20 0.44
TDP1 Q9NUW8 4/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPK1 P28482 4/20 0.44
KDM4E B2RXH2 3/20 0.44
CYP3A4 P08684 3/20 0.44
ALOX15 P16050 3/20 0.44
RECQL P46063 3/20 0.44
HSD17B10 Q99714 3/20 0.44
APEX1 P27695 3/20 0.44
BRCA1 P38398 2/20 0.44
THRB P10828 2/20 0.44
USP2 O75604 1/20 0.44
RAF1 P04049 1/20 0.44
TP53 P04637 1/20 0.44
CSNK2A2 P19784 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10526608 0.82 MAPT (0.49) MAPTMEN1KMT2AMAOAALDH1A1
SCHEMBL8900788 0.82 MAPT (0.51) MAPTMEN1KMT2AALDH1A1TTR
SCHEMBL10607330 0.82 TTR (0.44) MAPTMEN1KMT2ATDP1ALDH1A1
SCHEMBL5305956 0.82 MAPT (0.45) MAPTMEN1KMT2AMAOAHPGD
SCHEMBL3912083 0.81 TTR (0.55) MAPTMEN1KMT2AMAOATDP1
SCHEMBL17554244 0.79 TTR (0.53) MAPTMEN1KMT2AMAOATDP1
SCHEMBL6261936 0.79 PTPRC (0.56) MAPTMEN1KMT2AMAOAHPGD
SCHEMBL6260079 0.76 PTPRC (0.56) MAPTMEN1KMT2AMAOAHPGD
SCHEMBL11103011 0.75 ADORA2A (0.48) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL10529319 0.75 MAPT (0.49) MAPTMEN1KMT2AHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007022979-A2 MEDIATOR SYSTEMS FOR THE ELECTROCHEMICAL REDUCTION OF ORGANIC COMPOUNDS IN AN AQUEOUS SOLUTION DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2007-03-01 WO disclosed