Ornithine Aketoglutarate

Ornithine Aketoglutarate

SCHEMBL53032

CCC(N)(N)C(=O)O.NCCCC(N)C(=O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.58
NOS1 P29475 7/20 0.42
DDAH1 O94760 3/20 0.42
NOS2 P35228 7/20 0.41
NOS3 P29474 5/20 0.41
CYP2C19 P33261 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ARG2 P78540 4/20 0.41
ARG1 P05089 3/20 0.41
CYP1A2 P05177 2/20 0.40
TSHR P16473 2/20 0.40
CYP3A4 P08684 1/20 0.40
GLA P06280 1/20 0.40
NFKB1 P19838 1/20 0.40
APEX1 P27695 1/20 0.40
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ornithine SCHEMBL53033 1.00 GSR (0.58) GSRNOS1DDAH1NOS2NOS3
Lysine SCHEMBL3821051 0.92 GSR (0.62) GSRNOS1DDAH1NOS2NOS3
Lysine SCHEMBL3821052 0.92 GSR (0.62) GSRNOS1DDAH1NOS2NOS3
Ornithine Aketoglutarate SCHEMBL3000503 0.84 GSR (0.64) GSRNOS1DDAH1NOS2NOS3
Ornithine SCHEMBL6757036 0.84 GSR (0.64) GSRNOS1DDAH1NOS2NOS3
Ornithine SCHEMBL3000505 0.84 GSR (0.64) GSRNOS1DDAH1NOS2NOS3
Diaminopropanoic Acid SCHEMBL28533274 0.82 SLC1A3 (0.39) GSRCYP1A2
Ornithine Aketoglutarate SCHEMBL28452040 0.81 GSR (0.78) GSRNOS1DDAH1NOS2NOS3
Ornithine SCHEMBL3443860 0.81 GSR (0.78) GSRNOS1DDAH1NOS2NOS3
Ornithine SCHEMBL624782 0.81 GSR (0.86) GSRNOS1NOS2NOS3CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1614 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114015726-B Delivery, use and therapeutic application of CRISPR-CAS systems and compositions for targeting disorders and diseases with viral components 布罗德研究所有限公司 2025-06-24 CN disclosed
CN-113425857-B Delivery and use of CRISPR-CAS systems, vectors and compositions for liver targeting and treatment 布罗德研究所有限公司 2025-05-16 CN disclosed
CN-112840030-B Method for reducing nitrosamine content in tobacco using constitutive high affinity cationic efflux proteins 英美烟草(投资)有限公司 2025-05-06 CN disclosed
CN-113227366-B Method for regulating alkaloid content of plant 英美烟草(投资)有限公司 2025-04-29 CN disclosed
CN-110312805-B Method of 肯塔基大学研究基金会 2025-04-29 CN disclosed
CN-113272434-B Methods and means for modifying alkaloid content in plants 英美烟草(投资)有限公司 2025-04-08 CN disclosed
CN-110959039-B Novel CAS13B ortholog CRISPR enzymes and systems 博德研究所 2025-03-14 CN disclosed
CN-113939201-B BZIP transcription factors regulate the conversion of nicotine to nornicotine and reduce the levels of Tobacco Specific Nitrosamine (TSNA) precursors R·J·雷诺烟草公司 2025-03-11 CN disclosed
CN-119584864-A Improved enzymatic modification of phospholipids in food products 国际N&H丹麦有限公司 2025-03-07 CN disclosed
CN-113614235-B Method for reducing alkaloid content of tobacco plants 英美烟草(投资)有限公司 2025-02-11 CN disclosed
WO-2001077380-A2 METHOD FOR PREDICTING PREDISPOSITION TO A DISEASE ASSOCIATED WITH MUTATIONS IN A RPGR GENE MEDICAL RESEARCH COUNCIL (GB) 2001-10-18 WO disclosed
EP-1135410-A2 ANTENNAPEDIA HOMEODOMAIN HELIX 3 DERIVED TRANSLOCATION VECTORS Cyclacel Limited (GB) 2001-09-26 EP disclosed
EP-1118858-A2 Assay method Pfizer Limited (GB) 2001-07-25 EP disclosed
EP-1108360-A1 Method of improving dough and bread quality DANISCO A/S (DK) 2001-06-20 EP disclosed
WO-2001039602-A1 METHOD OF IMPROVING DOUGH AND BREAD QUALITY DANISCO A/S (DK) 2001-06-07 WO disclosed
EP-1097707-A1 Treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097706-A1 Phosphodiesterase inhibitors for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097719-A1 NEP inhibitors for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097718-A1 NPY antagonists for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
WO-2000029427-A2 ANTENNAPEDIA HOMEODOMAIN HELIX 3 DERIVED TRANSLOCATION VECTORS CYCLACEL LIMITED (GB) 2000-05-25 WO disclosed