Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97869 | 0.96 | POLB (0.40) | POLBCRHBPCRHR2MEN1KMT2A | |
| SCHEMBL97439 | 0.87 | POLB (0.42) | POLBMEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL97445 | 0.79 | POLB (0.43) | POLBMEN1KMT2AL3MBTL1DCTPP1 | |
| SCHEMBL96345 | 0.74 | POLB (0.35) | POLB | |
| SCHEMBL98519 | 0.67 | CHRM1 (0.37) | — | |
| SCHEMBL98295 | 0.67 | KMT2A (0.43) | MEN1KMT2AL3MBTL1ALDH1A1GAA | |
| SCHEMBL97993 | 0.66 | HCRTR1 (0.34) | POLBL3MBTL1TSHRALDH1A1GAA | |
| SCHEMBL98538 | 0.66 | CXCR4 (0.40) | POLBALDH1A1 | |
| SCHEMBL10568031 | 0.62 | POLB (0.61) | POLBMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL18002473 | 0.61 | CRHBP (0.38) | CRHBPCRHR2KMT2AL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |