⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530489 | 1.00 | — | — | |
| SCHEMBL18938894 | 0.91 | — | — | |
| SCHEMBL1982426 | 0.83 | — | — | |
| SCHEMBL1982425 | 0.83 | — | — | |
| SCHEMBL527709 | 0.81 | CYP1A2 (0.32) | — | |
| SCHEMBL529602 | 0.78 | — | — | |
| SCHEMBL2096618 | 0.73 | MAPT (0.31) | — | |
| SCHEMBL528091 | 0.73 | CYP1A2 (0.40) | — | |
| SCHEMBL331749 | 0.72 | ATM (0.31) | — | |
| SCHEMBL373857 | 0.72 | USP2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113937-A1 | IMPROVED CLEANING METHOD FOR MOLDS USED IN THE MANUFACTURING OF SILICONE HYDROGEL CONTACT LENSES | Novartis AG (CH) | 2017-01-11 | — | — | EP | claimed |
| WO-2015132277-A1 | IMPROVED CLEANING METHOD FOR MOLDS USED IN THE MANUFACTURING OF SILICONE HYDROGEL CONTACT LENSES | NOVARTIS AG (CH) | 2015-09-11 | — | — | WO | claimed |
| EP-2598937-A2 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | Novartis AG (CH) | 2013-06-05 | — | — | EP | claimed |
| WO-2012016097-A2 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2012-02-02 | — | — | WO | claimed |
| EP-3390498-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | Novartis AG (CH) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017103790-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | NOVARTIS AG (CH) | 2017-06-22 | — | — | WO | disclosed |
| EP-3113937-A1 | IMPROVED CLEANING METHOD FOR MOLDS USED IN THE MANUFACTURING OF SILICONE HYDROGEL CONTACT LENSES | Novartis AG (CH) | 2017-01-11 | — | — | EP | disclosed |
| WO-2015132277-A1 | IMPROVED CLEANING METHOD FOR MOLDS USED IN THE MANUFACTURING OF SILICONE HYDROGEL CONTACT LENSES | NOVARTIS AG (CH) | 2015-09-11 | — | — | WO | disclosed |