⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530488 | 0.78 | — | — | |
| SCHEMBL530489 | 0.78 | — | — | |
| SCHEMBL18938894 | 0.78 | — | — | |
| SCHEMBL1982425 | 0.76 | — | — | |
| SCHEMBL1960031 | 0.76 | MAPT (0.30) | — | |
| SCHEMBL1982426 | 0.76 | — | — | |
| SCHEMBL30306612 | 0.74 | USP2 (0.47) | — | |
| SCHEMBL331865 | 0.74 | — | — | |
| SCHEMBL23493061 | 0.72 | TSHR (0.38) | — | |
| SCHEMBL508852 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3113937-A1 | IMPROVED CLEANING METHOD FOR MOLDS USED IN THE MANUFACTURING OF SILICONE HYDROGEL CONTACT LENSES | Novartis AG (CH) | 2017-01-11 | — | — | EP | claimed |
| WO-2015132277-A1 | IMPROVED CLEANING METHOD FOR MOLDS USED IN THE MANUFACTURING OF SILICONE HYDROGEL CONTACT LENSES | NOVARTIS AG (CH) | 2015-09-11 | — | — | WO | claimed |
| US-8163206-B2 | Method for making silicone hydrogel contact lenses | NOVARTIS AG (CH) | 2012-04-24 | — | — | US | claimed |
| US-20100258961-A1 | Method for making silicone hydrogel contact lenses | ALCON INC. (CH) | 2010-10-14 | — | — | US | claimed |
| US-10513628-B2 | Silicone hydrogel lenses with water-rich surfaces | NOVARTIS AG (CH) | 2019-12-24 | — | — | US | disclosed |
| US-20190055427-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC. (CH) | 2019-02-21 | — | — | US | disclosed |
| US-10131815-B2 | Silicone hydrogel lenses with water-rich surfaces | NOVARTIS AG (CH) | 2018-11-20 | — | — | US | disclosed |
| US-20180044549-A1 | SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES | ALCON INC. (CH) | 2018-02-15 | — | — | US | disclosed |
| EP-2598937-A2 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | Novartis AG (CH) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012016097-A2 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2012-02-02 | — | — | WO | disclosed |