Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.48 |
| ▸ | AXL | P30530 | 8/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186596 | 0.94 | MET (0.53) | METAXLKDRPDGFRASRC | |
| SCHEMBL5304436 | 0.88 | MET (0.52) | METAXLKDRSRCTGFBR1 | |
| SCHEMBL5307620 | 0.85 | MET (0.53) | METAXLKDR | |
| SCHEMBL3911419 | 0.82 | MET (0.60) | METAXLKDRPDGFRAMERTK | |
| SCHEMBL4774400 | 0.78 | AXL (0.51) | METAXLKDRPDGFRASRC | |
| SCHEMBL5154071 | 0.77 | MET (0.41) | METKDR | |
| SCHEMBL374207 | 0.77 | AXL (0.55) | METAXLKDRPDGFRAMERTK | |
| SCHEMBL15542224 | 0.76 | MET (0.39) | METAXLKDRMERTK | |
| SCHEMBL5150627 | 0.75 | MET (0.39) | METKDR | |
| SCHEMBL1396734 | 0.75 | AXL (0.49) | METAXLKDRPDGFRASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007033196-A1 | MET KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-03-22 | — | — | WO | disclosed |