Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 5/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2999996 | 0.92 | CES2 (0.53) | KMT2AMAPTCES2CES1MEN1 | |
| SCHEMBL2992800 | 0.92 | CES2 (0.53) | KMT2AMAPTCES2CES1MEN1 | |
| SCHEMBL29770831 | 0.92 | CES2 (0.53) | KMT2AMAPTCES2CES1MEN1 | |
| SCHEMBL15188717 | 0.92 | CES2 (0.53) | KMT2AMAPTCES2CES1MEN1 | |
| Methylamine SCHEMBL20788005 | 0.89 | CES2 (0.50) | KMT2AMAPTCES2CES1MEN1 | |
| SCHEMBL15316792 | 0.87 | CES2 (0.38) | CES2CES1 | |
| Trimethylammonium SCHEMBL467213 | 0.87 | CES2 (0.48) | KMT2AMAPTCES2CES1MEN1 | |
| Dimethylamine SCHEMBL20788004 | 0.87 | KMT2A (0.50) | KMT2AMAPTCES2CES1MEN1 | |
| Dimethylamine SCHEMBL20788003 | 0.87 | KMT2A (0.50) | KMT2AMAPTCES2CES1MEN1 | |
| Trimethylammonium SCHEMBL466595 | 0.87 | CES2 (0.48) | KMT2AMAPTCES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012980-A1 | TOBACCO WITH AN INCREASED LEVEL OF NATURAL TAR DILUTENTS | PHILIP MORRIS PRODUCTS S.A. (CH) | 2007-02-01 | — | — | WO | claimed |