Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305666 | 0.87 | KMT2A (0.45) | CES2CES1 | |
| SCHEMBL24124706 | 0.84 | ALDH1A1 (0.37) | CES2CES1ALDH1A1 | |
| SCHEMBL11604570 | 0.83 | CES2 (0.39) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL27626987 | 0.81 | FFAR3 (0.48) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL27970840 | 0.81 | CYP1A2 (0.44) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL9738062 | 0.81 | FFAR3 (0.48) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL25610796 | 0.81 | CES1 (0.38) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL2992800 | 0.79 | CES2 (0.53) | CES2CES1 | |
| SCHEMBL2999996 | 0.79 | CES2 (0.53) | CES2CES1 | |
| SCHEMBL29770831 | 0.79 | CES2 (0.53) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-9695117-B2 | Fluorosurfactants in pesticides | MERCK PATENT GMBH (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20160122297-A1 | FLUOROSURFACTANTS IN PESTICIDES | MERCK PATENT GMBH (DE) | 2016-05-05 | — | — | US | disclosed |
| US-20150210830-A1 | SURFACTANT MIXTURES | MERCK PATENT GMBH (DE) | 2015-07-30 | — | — | US | disclosed |
| US-20130269568-A1 | DERIVATIVES FOR PERFLUOROALKOXY SULFOSUCCINATES AS SURFACTANTS | MERCK PATENT GMBH (DE) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122297-A1 | FLUOROSURFACTANTS IN PESTICIDES | PFAS, DDT, SGMS2 | CES2 218/4885CES1 296/4885HDAC3 1397/4885 |
| US-20130269568-A1 | DERIVATIVES FOR PERFLUOROALKOXY SULFOSUCCINATES AS SURFACTANTS | PFAS, SFXN3, FGB | CES2 1589/4885CES1 740/4885HDAC3 3835/4885 |
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | CES2 1139/4885CES1 993/4885HDAC3 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.