Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20240266 | 0.92 | LTA4H (0.48) | CHEK1 | |
| SCHEMBL21605932 | 0.84 | KDM1A (0.44) | CHEK1KDM1AACP1 | |
| SCHEMBL19377884 | 0.84 | CCNT1 (0.43) | KDM1AACP1 | |
| SCHEMBL21605922 | 0.84 | KDM1A (0.44) | CHEK1KDM1AACP1 | |
| SCHEMBL8178820 | 0.84 | KMT2A (0.49) | CHEK1KDM1AACP1 | |
| SCHEMBL5605238 | 0.80 | PRMT5 (0.45) | KDM1A | |
| SCHEMBL22414314 | 0.80 | NPC1 (0.47) | KDM1A | |
| SCHEMBL14740667 | 0.79 | KMT2A (0.49) | — | |
| SCHEMBL13769159 | 0.79 | KDM1A (0.47) | CHEK1KDM1A | |
| SCHEMBL240037 | 0.77 | NPC1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2597955-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | OncoTherapy Science, Inc. (JP) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012016082-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2012-02-02 | — | — | WO | disclosed |