Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 10/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308839 | 0.92 | SCD (0.49) | SMN1; SMN2SCDPTGESRAB9AHTT | |
| SCHEMBL5307042 | 0.89 | SCD (0.42) | F10SCDPTGESNPC1RAB9A | |
| SCHEMBL5310358 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2TDP1F10NAMPTNPC1 | |
| SCHEMBL5309749 | 0.85 | SCD (0.41) | SCDPTGESKMT2A | |
| SCHEMBL5307539 | 0.85 | SCD (0.47) | SCD | |
| SCHEMBL5306749 | 0.85 | F10 (0.47) | SMN1; SMN2TDP1F10SCD | |
| SCHEMBL5309153 | 0.84 | CYP1A2 (0.43) | SMN1; SMN2SCDKMT2A | |
| SCHEMBL5315061 | 0.83 | SCD (0.45) | SMN1; SMN2TDP1F10SCDPTGES | |
| SCHEMBL5309835 | 0.82 | SCD (0.51) | SCD | |
| SCHEMBL5314447 | 0.82 | SCD (0.46) | SCDPTGESKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046867-A2 | PIPERIDINE DERIVATIVES AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2007-04-26 | — | — | WO | disclosed |