Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | TGM2 | P21980 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8243065 | 0.92 | MAPT (0.51) | PTGER4CTSLCTSSTGM2CTSB | |
| SCHEMBL5303063 | 0.92 | MAPT (0.51) | PTGER4CTSLCTSSTGM2CTSB | |
| SCHEMBL5300239 | 0.87 | SIRT2 (0.59) | PTGER4CTSLCTSSCTSBCTSK | |
| SCHEMBL8245500 | 0.87 | SIRT2 (0.59) | PTGER4CTSLCTSSCTSBCTSK | |
| SCHEMBL29398404 | 0.86 | FOLH1 (0.62) | TGM2 | |
| SCHEMBL5297597 | 0.83 | MEN1 (0.53) | CTSLCTSSCTSBCTSKSIRT5 | |
| SCHEMBL8237024 | 0.83 | MEN1 (0.53) | CTSLCTSSCTSBCTSKSIRT5 | |
| SCHEMBL12082261 | 0.83 | FOLH1 (0.67) | TGM2 | |
| SCHEMBL5302755 | 0.82 | MAPT (0.59) | PTGER4CTSLCTSSCTSBCTSK | |
| SCHEMBL8242070 | 0.82 | MAPT (0.59) | PTGER4CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027742-A2 | SMALL MOLECULE INTEGRIN α2βl/GPIa-IIa ANTAGONISTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-03-08 | — | — | WO | claimed |
| WO-2007027742-A2 | SMALL MOLECULE INTEGRIN α2βl/GPIa-IIa ANTAGONISTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-03-08 | — | — | WO | disclosed |