Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 8/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5297597 | 1.00 | MEN1 (0.53) | MEN1RECQLKMT2ACTSKCAPN1 | |
| SCHEMBL8243065 | 0.92 | MAPT (0.51) | CTSKCTSSCTSLCTSBPSMB5 | |
| SCHEMBL5303063 | 0.92 | MAPT (0.51) | CTSKCTSSCTSLCTSBPSMB5 | |
| SCHEMBL21981385 | 0.84 | CAPN1 (0.59) | MEN1RECQLKMT2ACTSKCAPN1 | |
| SCHEMBL20669109 | 0.84 | CTSK (0.58) | MEN1RECQLKMT2ACTSKCAPN1 | |
| SCHEMBL21981287 | 0.84 | CTSK (0.58) | MEN1RECQLKMT2ACTSKCAPN1 | |
| SCHEMBL5307097 | 0.83 | PTGER4 (0.56) | CTSKSIRT5CTSSCTSLCTSB | |
| SCHEMBL8242070 | 0.83 | MAPT (0.59) | CTSKCTSSCTSLCTSBPSMB5 | |
| SCHEMBL5302755 | 0.83 | MAPT (0.59) | CTSKCTSSCTSLCTSBPSMB5 | |
| SCHEMBL22834040 | 0.83 | MAPT (0.59) | CAPN1CAPN2KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027742-A2 | SMALL MOLECULE INTEGRIN α2βl/GPIa-IIa ANTAGONISTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-03-08 | — | — | WO | disclosed |