Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.33 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21107343 | 0.81 | LPL (0.42) | LPLLIPGCA1CA2ERN1 | |
| SCHEMBL22536178 | 0.80 | ENPP2 (0.46) | LPLLIPGCA1CA2ALDH1A1 | |
| SCHEMBL104085 | 0.78 | LPL (0.58) | LPLLIPGCA1CA2TRPV1 | |
| SCHEMBL26293815 | 0.77 | CA1 (0.57) | CA1CA2ENPP2HTT | |
| SCHEMBL5953336 | 0.76 | LPL (0.50) | LPLLIPGCA1CA2ALDH1A1 | |
| SCHEMBL21449321 | 0.75 | ENPP2 (0.48) | LPLLIPGALDH1A1ENPP2LMNA | |
| SCHEMBL21315979 | 0.75 | ORAI1 (0.48) | LPLLIPGALDH1A1TRPV1LMNA | |
| SCHEMBL20283963 | 0.75 | LPL (0.34) | LPLLIPGCA1CA2ENPP2 | |
| SCHEMBL1722636 | 0.74 | PCSK9 (0.45) | CA1CA2ALDH1A1LYPLA1LYPLA2 | |
| SCHEMBL29144771 | 0.74 | LPL (0.36) | LPLLIPGCA1CA2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034282-A2 | DIARYL-IMIDAZOLE COMPOUNDS CONDENSED WITH A HETEROCYCLE AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |