Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986721 | 0.74 | KDM4E (0.50) | — | |
| SCHEMBL1456807 | 0.71 | GOT1 (0.46) | NPY5RGOT1 | |
| SCHEMBL30792004 | 0.71 | GOT1 (0.46) | NPY5RGOT1 | |
| SCHEMBL29442588 | 0.71 | GOT1 (0.46) | NPY5RGOT1 | |
| SCHEMBL1925074 | 0.68 | GOT1 (0.33) | NPY5RGOT1 | |
| SCHEMBL579172 | 0.68 | TP53 (0.32) | NPY5RGOT1 | |
| SCHEMBL584299 | 0.67 | HDAC4 (0.35) | GOT1 | |
| SCHEMBL317129 | 0.67 | GOT1 (0.32) | GOT1 | |
| SCHEMBL13911004 | 0.67 | GOT1 (0.42) | NPY5RGOT1 | |
| SCHEMBL8135893 | 0.65 | KMT2A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784224-A2 | EGFR KINASE INHIBITOR COMBINATIONS FOR TREATING RESPIRATORY AND GASTROINTESTINAL DISORDERS | Boehringer Ingelheim International GmbH (DE) | 2007-05-16 | — | — | EP | claimed |
| WO-2006015775-A2 | EGFR KINASE INHIBITOR COMBINATIONS FOR TREATING RESPIRATORY AND GASTROINTESTINAL DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-02-16 | — | — | WO | claimed |
| US-6080763-A | INHIBIT THE RELEASE OF INFLAMMATORY CYTOKINES, E.G., TUMOR NECROSIS FACTOR AND INTERLEUKIN-1; USEFUL TO TREAT CHRONIC INFLAMMATORY DISEASE; AUTOIMMUNE DISEASES, E.G. RHEUMATOID ARTHRITIS, OSTEOPOROSIS; PYRAZOLYLUREAS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-06-27 | — | — | US | claimed |
| CN-113993861-B | Phenyl ethers and anilines of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117956990-A | Compositions and methods for treating lipomatous pain | 拉结尔治疗有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117751106-A | Novel triazole-pyridine substituted pyrrolidinyl and tetrahydro-2H-pyranylacetic acid compounds as LPA antagonists | 唯久生物技术(苏州)有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-3083639-B1 | CYCLIC SULFONE AND SULFOXIMINE ANALOGS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2019-05-29 | — | — | EP | disclosed |