Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPRB | P23467 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002710 | 0.87 | EPHX2 (0.60) | NAMPTHPGDLMNAHTTSMN1; SMN2 | |
| SCHEMBL19553731 | 0.87 | NAMPT (0.48) | NAMPTLMNACA1CA2L3MBTL1 | |
| SCHEMBL22407524 | 0.86 | CA1 (0.55) | NAMPTLMNACA1CA2L3MBTL1 | |
| SCHEMBL5308235 | 0.85 | PPARA (0.55) | NAMPTLMNASMN1; SMN2CA1CA2 | |
| SCHEMBL4887187 | 0.85 | NAMPT (0.51) | NAMPTLMNACA1CA2L3MBTL1 | |
| SCHEMBL4892802 | 0.85 | CA1 (0.58) | NAMPTLMNACA1CA2L3MBTL1 | |
| SCHEMBL4891161 | 0.84 | HPGD (0.52) | NAMPTHPGDLMNACA1CA2 | |
| SCHEMBL3180689 | 0.83 | L3MBTL1 (0.61) | NAMPTCA1CA2L3MBTL1GAA | |
| SCHEMBL19640466 | 0.83 | NAMPT (0.49) | NAMPTLMNACA1CA2L3MBTL1 | |
| SCHEMBL20946387 | 0.82 | LMNA (0.58) | NAMPTLMNACA1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047575-A2 | PHARMACOLOGICAL TREATMENTS FOR SLEEP-RELATED BREATHING DISORDERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-04-26 | — | — | WO | disclosed |