Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.45 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27847070 | 0.83 | HRH1 (0.48) | HRH1HTR2ACNR1CNR2RIPK1 | |
| SCHEMBL50795 | 0.79 | KCNN4 (0.41) | HRH1TAAR1CYP2D6LMNACYP1A2 | |
| SCHEMBL907893 | 0.79 | CYP2D6 (0.39) | RIPK1TAAR1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL9797822 | 0.78 | KIF11 (0.53) | HRH1HTR2ACNR1CNR2 | |
| SCHEMBL29926447 | 0.75 | CNR1 (0.49) | HRH1HTR2ACNR1CNR2RIPK1 | |
| SCHEMBL27864318 | 0.75 | CNR1 (0.47) | HRH1HTR2ACNR1CNR2RIPK1 | |
| SCHEMBL1851361 | 0.75 | CNR1 (0.49) | HRH1HTR2ACNR1CNR2RIPK1 | |
| SCHEMBL11137800 | 0.73 | HRH1 (0.52) | HRH1HTR2ARIPK1TAAR1KCNH2 | |
| SCHEMBL1820058 | 0.72 | KCNN4 (0.39) | TAAR1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11143288 | 0.71 | HRH1 (0.50) | HRH1HTR2ACNR1CNR2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211272-B1 | BUTADIENE/ISOPRENE/AROMATIC VINYL HYDROCARBON SEVENBLOCK COPOLYMER AND THE PREPARING METHOD THEREOF | CHINA PETROCHEMICAL CORP (CN) | 2007-09-12 | — | — | EP | disclosed |
| EP-1211272-A1 | BUTADIENE/ISOPRENE/AROMATIC VINYL HYDROCARBON SEVENBLOCK COPOLYMER AND THE PREPARING METHOD THEREOF | China Petro-Chemical Corporation (CN) | 2002-06-05 | — | — | EP | disclosed |
| EP-1092732-A2 | Preparation of poly(meth)acrylates by anionic polymerisation in the presence of specific additives in toluene at higher temperatures | RÖHM GMBH (DE) | 2001-04-18 | — | — | EP | disclosed |