Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50795 | 0.79 | KCNN4 (0.41) | CYP2D6ALDH1A1CYP2C19MEN1KMT2A | |
| SCHEMBL5307273 | 0.79 | HRH1 (0.45) | CYP2D6ALDH1A1CYP2C19RIPK1MEN1 | |
| SCHEMBL6681496 | 0.77 | TAAR1 (0.50) | CYP2D6ALDH1A1CYP2C19HSD17B10RIPK1 | |
| SCHEMBL8006703 | 0.76 | KCNN4 (0.41) | CYP2D6CYP2C19HSD17B10MEN1KMT2A | |
| SCHEMBL12356880 | 0.75 | ALDH1A1 (0.41) | CYP2D6ALDH1A1CYP2C19HSD17B10RIPK1 | |
| SCHEMBL872854 | 0.73 | CYP2C19 (0.46) | CYP2D6ALDH1A1CYP2C19HSD17B10RIPK1 | |
| Ammonia Solution, Strong SCHEMBL6230799 | 0.73 | ALDH1A1 (0.39) | CYP2D6ALDH1A1CYP2C19HSD17B10RIPK1 | |
| SCHEMBL17965831 | 0.73 | CYP2D6 (0.35) | CYP2D6ALDH1A1CYP2C19HSD17B10RIPK1 | |
| SCHEMBL8416734 | 0.72 | KIF11 (0.41) | MEN1KMT2ATAAR1KIF11 | |
| SCHEMBL11436523 | 0.72 | KCNN4 (0.39) | CYP2D6ALDH1A1CYP2C19HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015349-A1 | End-capped polymer chains and products thereof | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2011-01-20 | — | — | US | claimed |
| US-20080275202-A1 | End-Capped Polymer Chains and Products Thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2008-11-06 | — | — | US | claimed |
| US-20050176903-A1 | End-capped polymer chains and products thereof | MASSACHUSETTS LOWELL, UNIVERSITY OF | 2005-08-11 | — | — | US | claimed |