Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051513 | 0.84 | HPGDS (0.55) | KAT6ANPC1CTSDSMN1; SMN2CA12 | |
| SCHEMBL2850796 | 0.84 | HMGCR (0.51) | HMGCRNPC1SMN1; SMN2CA9RAB9A | |
| SCHEMBL12780447 | 0.83 | F2R (0.44) | KMT2AGAAMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL878658 | 0.83 | NPC1 (0.64) | HMGCRNPC1CTSDSMN1; SMN2RAB9A | |
| SCHEMBL10954882 | 0.83 | KAT6A (0.52) | KAT6ANPC1CTSDSMN1; SMN2CA12 | |
| SCHEMBL29738645 | 0.83 | NPC1 (0.64) | HMGCRNPC1CTSDSMN1; SMN2RAB9A | |
| SCHEMBL8523809 | 0.83 | KAT6A (0.57) | KAT6ANPC1CTSDSMN1; SMN2CA12 | |
| SCHEMBL27570696 | 0.83 | NPC1 (0.51) | KAT6ANPC1CTSDSMN1; SMN2CA12 | |
| SCHEMBL13089201 | 0.82 | HMGCR (0.50) | HMGCRNPC1CTSDCA12CA1 | |
| SCHEMBL3661643 | 0.82 | HPGD (0.54) | HMGCRNPC1SMN1; SMN2RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007044796-A2 | PYRIDAZINONE COMPOUNDS AS CALCILYTICS | NPS PHARMACEUTICALS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |