Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 16/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5306689 | 0.82 | SLC6A4 (0.45) | SLC6A3SLC6A4SLC6A2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL11125131 | 0.77 | SLC6A4 (0.48) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5309463 | 0.75 | SLC6A3 (0.46) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5308752 | 0.75 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5153687 | 0.75 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5310520 | 0.74 | SLC6A3 (0.56) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL5302726 | 0.72 | SLC6A3 (0.65) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL31410053 | 0.71 | SLC6A4 (0.39) | SLC6A3SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL17186925 | 0.69 | PRKAB2 (0.44) | SLC6A3SLC6A4PRKAB2PRKAG1PRKAA2 | |
| Hydrochloric Acid SCHEMBL5306058 | 0.69 | SLC6A3 (0.67) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007041677-A9 | SOFT TISSUE IMPLANTS AND DRUG COMBINATION COMPOSITIONS, AND USE THEREOF | COMBINATORX INC (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007041593-A2 | ANTI-SCARRING DRUG COMBINATIONS AND USE THEREOF | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007041584-A2 | IMPLANTABLE SENSORS, IMPLANTABLE PUMPS, AND ANTI-SCARRING DRUG COMBINATIONS | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007041677-A2 | SOFT TISSUE IMPLANTS AND DRUG COMBINATION COMPOSITIONS, AND USE THEREOF | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2005079284-A2 | METHODS AND REAGENTS FOR THE TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH INCREASED LEVELS OF PROINFLAMMATORY CYTOKINES | COMBINATORX, INCORPORATED (US) | 2005-09-01 | — | — | WO | disclosed |