Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5308286

CCOC(=O)/C(C)=C(/CC)C(=O)OCC.N

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.44
LMNA P02545 1/20 0.44
HSD17B10 Q99714 1/20 0.44
GLO1 Q04760 1/20 0.43
SOAT1 P35610 1/20 0.42
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TSHR P16473 2/20 0.38
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
EGLN1 Q9GZT9 1/20 0.36
TRPA1 O75762 1/20 0.34
CYP2D6 P10635 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1593260 0.98 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10GLO1SOAT1
SCHEMBL1593259 0.98 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10GLO1SOAT1
SCHEMBL5611292 0.87 MAPT (0.41) ALDH1A1LMNAHSD17B10GLO1SOAT1
Ammonia Solution, Strong SCHEMBL29049234 0.85 SOAT1 (0.50) ALDH1A1LMNAHSD17B10GLO1SOAT1
Ammonia Solution, Strong SCHEMBL4866860 0.85 SOAT1 (0.50) ALDH1A1LMNAHSD17B10GLO1SOAT1
SCHEMBL28323427 0.85 GLO1 (0.36) ALDH1A1LMNAHSD17B10GLO1SOAT1
SCHEMBL305144 0.84 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GLO1SOAT1
SCHEMBL29201842 0.84 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GLO1SOAT1
SCHEMBL28688125 0.84 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GLO1SOAT1
SCHEMBL29201836 0.84 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10GLO1SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007044632-A1 IMPROVED CURABLE FIBERGLASS BINDER COMPRISING A β- AMINO-ESTER OR β-AMINO-AMIDE CONJUGATE ADDITION PRODUCT JOHNS MANVILLE (US) 2007-04-19 WO claimed
US-20070082208-A1 Curable fiberglass binder comprising a beta-amino-ester or beta-amino-amide conjugate addition product JOHNS MANVILLE 2007-04-12 US claimed
WO-2007044632-A1 IMPROVED CURABLE FIBERGLASS BINDER COMPRISING A β- AMINO-ESTER OR β-AMINO-AMIDE CONJUGATE ADDITION PRODUCT JOHNS MANVILLE (US) 2007-04-19 WO disclosed
US-20070082208-A1 Curable fiberglass binder comprising a beta-amino-ester or beta-amino-amide conjugate addition product JOHNS MANVILLE 2007-04-12 US disclosed