Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500244 | 1.00 | ALOX5 (0.57) | ALOX5HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11697365 | 0.82 | HPGD (0.60) | ALOX5HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29120812 | 0.81 | ALOX5 (0.57) | ALOX5HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11587666 | 0.81 | ALOX5 (0.65) | ALOX5HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8275741 | 0.79 | HPGD (0.65) | ALOX5HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29500235 | 0.79 | RAB9A (0.50) | HPGDHSD17B10APEX1RAB9AALDH1A1 | |
| SCHEMBL11585822 | 0.78 | HPGD (0.60) | ALOX5HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21802341 | 0.77 | ALOX5 (0.57) | ALOX5HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29500257 | 0.76 | CYP1A2 (0.54) | HPGDCYP1A2CYP2C19HSD17B10RAB9A | |
| SCHEMBL11165753 | 0.75 | ALOX5 (0.62) | ALOX5HPGDCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045962-A2 | NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |