Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309948 | 0.90 | MEN1 (0.61) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5309416 | 0.88 | MEN1 (0.52) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5305542 | 0.88 | MEN1 (0.54) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5308927 | 0.86 | MEN1 (0.52) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5310233 | 0.83 | HIF1A (0.52) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5308968 | 0.83 | MEN1 (0.49) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5311312 | 0.81 | KMT2A (0.51) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5308223 | 0.78 | MEN1 (0.52) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5304888 | 0.76 | MEN1 (0.56) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL5305353 | 0.76 | KMT2A (0.48) | MEN1KMT2ARXFP1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |