Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309245 | 0.89 | MEN1 (0.45) | THRATHRBMEN1KMT2ARXFP1 | |
| SCHEMBL5308604 | 0.87 | MEN1 (0.43) | THRATHRBMEN1KMT2ARXFP1 | |
| SCHEMBL5312251 | 0.85 | MEN1 (0.48) | MEN1KMT2ARXFP1KDM4EHIF1A | |
| SCHEMBL5312400 | 0.85 | MEN1 (0.48) | THRATHRBMEN1KMT2ARXFP1 | |
| SCHEMBL5312539 | 0.84 | MEN1 (0.46) | THRATHRBMEN1KMT2ARXFP1 | |
| SCHEMBL5308580 | 0.83 | HIF1A (0.46) | MEN1KMT2AKDM4EHIF1AEGLN1 | |
| SCHEMBL5309396 | 0.79 | EGLN1 (0.43) | MEN1KMT2ARXFP1KDM4EHIF1A | |
| SCHEMBL5313516 | 0.78 | EGLN3 (0.43) | MEN1KMT2ARXFP1KDM4EHIF1A | |
| SCHEMBL5310233 | 0.78 | HIF1A (0.52) | THRATHRBMEN1KMT2ARXFP1 | |
| SCHEMBL5305537 | 0.78 | TDP1 (0.45) | MEN1KMT2ARXFP1HIF1AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |